Personnel resources can introduce uncertainty in the operational processes. Constructed personnel rosters can be disrupted and render infeasible rosters. Feasibility has to be restored by adapting the original announced personnel rosters. In this paper, an Artificial Immune System for the nurse re-rostering problem is presented. The proposed algorithm uses problem-specific and even roster-specific mechanisms which are inspired on the vertebrate immune system. We observe the performance of the different algorithmic components and compare the proposed procedure with the existing literature.
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