A custom pack combines medical disposable items into a single sterile package that is used for surgical procedures. Although custom packs are gaining importance in hospitals due to their potential benefits in reducing surgery setup times, little is known on methodologies to configure them, especially if the number of medical items, procedure types and surgeons is large. In this paper, we propose a mathematical programming approach to guide hospitals in developing or reconfiguring their custom packs. In particular, we are interested in minimising points of touch, which we define as a measure for physical contact between staff and medical materials. Starting from an integer non-linear programming model, we develop both an exact linear programming (LP) solution approach and an LP-based heuristic. Next, we also describe a simulated annealing approach to benchmark the mathematical programming methods. A computational experiment, based on real data of a medium-sized Belgian hospital, compares the optimised results with the performance of the hospital's current configuration settings and indicates how to improve future usage. Next to this base case, we introduce scenarios in which we examine to what extent the results are sensitive for waste, i.e. adding more items to the custom pack than is technically required for some of the custom pack's procedures, since this can increase its applicability towards other procedures. We point at some interesting insights that can be taken up by the hospital management to guide the configuration and accompanying negotiation processes.

Support Vector Machines are methods that stem from Artificial Intelligence and attempt to learn the relation between data inputs and one or multiple output values. However, the application of these methods has barely been explored in a project control context. In this paper, a forecasting analysis is presented that compares the proposed Support Vector Regression model with the best performing Earned Value and Earned Schedule methods. The parameters of the SVM are tuned using a cross-validation and grid search procedure, after which a large computational experiment is conducted. The results show that the Support Vector Machine Regression outperforms the currently available forecasting methods. Additionally, a robustness experiment has been set up to investigate the performance of the proposed method when the discrepancy between training and test set becomes larger.

In this paper, the extended Resource Renting Problem (RRP/extended) is presented. The RRP/extended is a time-constrained project scheduling problem, in which the total project cost is minimised. In the RRP/extended, this total project cost is determined by a number of extra costs, which are defined in this paper. These costs are based on the costs that are used in the traditional Resource Renting Problem and the Total Adjustment Cost Problem. Therefore, the RRP/extended represents a union of these two problems. To solve the RRP/extended, a scatter search is developed. The building blocks of this scatter search are specifically designed for the RRP/extended. We introduce two crossovers and an improvement method. The efficiency of these building blocks will be shown in the paper. Furthermore, a sensitivity analysis is presented in which the five costs have diverse values.

In this paper the Resource Renting Problem with Overtime (RRP/overtime) is presented. The RRP/overtime is a new problem in which the assumptions of the basic RRP are combined with the possibility to schedule (parts of) activities during overtime. The addition of this extension increases the applicability of the RRP to real world problems. This paper also presents a solution technique for this extension of the resource renting problem. The solution procedure uses a scatter search heuristic to optimize a priority list, which is then in turn used by a schedule generation scheme (PatSGS). A variation on this schedule generation scheme is also used in dedicated local search procedures. The third contribution of this research is a new lower bound for the RRP/overtime problem, which is used to evaluate the results of the proposed heuristic solution method.

When scheduling projects under resource constraints, assumptions are typically made with respect to the resource availability. In resource scheduling problems important assumptions are made with respect to the resource requirements. As projects are typically labour intensive, the underlying (personnel) resource scheduling problems tend to be complex due to different rules and regulations. In this paper, we aim to integrate these two interrelated scheduling problems to minimise the overall cost. For that purpose, we propose an exact algorithm for the project staffing with resource scheduling constraints. Detailed computational experiments are presented to evaluate different branching rules and pruning strategies and to compare the proposed procedure with other optimisation techniques.