Vanhaeren, MichielGijsbers, RikVan Dyck, WalterHuys, IsabelleSimoens, Steven2025-09-102025-09-102025-09-102025-081359-6446https://doi.org/10.1016/j.drudis.2025.104459https://repository.vlerick.com/handle/20.500.12127/7731Advanced therapy medicinal products (ATMPs) are a unique class of biological medicines that are based on cells, genes, or tissues. Searching four databases, this analysis identified 2008 trials that investigated ATMPs and characterised them according to various characteristics, such as the sponsor type and phase of clinical development. This characterisation revealed that the market for ATMPs is maturing in terms of the number of products in development, the diseases being targeted, and the technologies being pursued. This characterisation is meant to help further the discussion on the ever-growing clinical trial landscape of ATMPs and inform healthcare payers.en32 Biomedical and Clinical Sciences3204 ImmunologyClinical Trials and Supportive ActivitiesClinical ResearchAdvanced Therapy Medicinal Product (ATMP)ATMPCell TherapyGene TherapyClinical TrialPipeline AnalysisMarket AccessDrug Discovery Today31183