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    Basic science as a prescription for breakthrough inventions in the pharmaceutical industry

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    Publication type
    Journal article with impact factor
    Author
    Della Malva, Antonio
    Kelchtermans, Stijn
    Leten, Bart
    Veugelers, Reinhilde
    Publication Year
    2015
    Journal
    Journal of Technology Transfer
    Publication Volume
    40
    Publication Issue
    4
    Publication Begin page
    670
    Publication End page
    695
    
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    Abstract
    This analysis contributes to the understanding of the role of basic science in generating breakthrough inventions in the pharmaceutical industry. Recognizing the within-firm heterogeneity of inventive activities, we look not only at the firm level, but also at the firm-technology level for characteristics determining breakthroughs. A key finding is that firms pursuing basic science are more likely to produce breakthrough inventions. At the same time, doing more basic science in science disciplines that are closely linked to a given technology domain does not increase the likelihood of BTs in that particular technology. The insignificance of basic science intensity at the technology level, coupled to the significance at the firm level, suggests that the breakthrough rewards from science capacity are not reaped in the technology areas immediately involved in basic science, but in other areas of the technology portfolio of the firm. Our findings are consistent with the view of science as a map to span processes of local search and the wider applicability of scientific insights.
    Keyword
    Breakthrough Invention, Pharmaceutical Industry, Basic Science
    Knowledge Domain/Industry
    Operations & Supply Chain Management
    DOI
    10.1007/s10961-014-9362-y
    URI
    http://hdl.handle.net/20.500.12127/5053
    ae974a485f413a2113503eed53cd6c53
    10.1007/s10961-014-9362-y
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