Advanced therapy medicinal products are coming of age: A pipeline analysis of the clinical trial landscape
Vanhaeren, Michiel Gijsbers, Rik Huys, Isabelle Simoens, Steven
Vanhaeren, Michiel
Gijsbers, Rik
Huys, Isabelle
Simoens, Steven
Publication Type
Journal article with impact factor
Editor
Supervisor
Publication Year
2025-08
Journal
Drug Discovery Today
Book
Publication Volume
30
Publication Issue
10
Publication Begin page
104459
Publication End page
104459
Publication Number of pages
Collections
Abstract
Advanced therapy medicinal products (ATMPs) are a unique class of biological medicines that are based on cells, genes, or tissues. Searching four databases, this analysis identified 2008 trials that investigated ATMPs and characterised them according to various characteristics, such as the sponsor type and phase of clinical development. This characterisation revealed that the market for ATMPs is maturing in terms of the number of products in development, the diseases being targeted, and the technologies being pursued. This characterisation is meant to help further the discussion on the ever-growing clinical trial landscape of ATMPs and inform healthcare payers.
Research Projects
Organizational Units
Journal Issue
Keywords
32 Biomedical and Clinical Sciences, 3204 Immunology, Clinical Trials and Supportive Activities, Clinical Research, Advanced Therapy Medicinal Product (ATMP), ATMP, Cell Therapy, Gene Therapy, Clinical Trial, Pipeline Analysis, Market Access